Research

UC San Diego Health System is a hub of translational medicine, where gifted professionals work together across disciplines and collaborate to deliver new discoveries to our patients. In fact, our patients are often the first to benefit from novel treatments that later become the standard of care worldwide.

UC San Diego’s research funding for FY10 topped $1 billion for the first time in our university’s history. In the same year, combined direct and indirect research funding to Health Sciences faculty alone totaled more than $540 million.

Publications

bullet Scientific Articles in Surgery

View titles and abstracts of scientific articles at PubMed written by UC San Diego Health System surgeons.

Current Research

  • Optimization of RNA Extraction from CSF Exosome for Expression Array Analysis
  • A retrospective review of Abdominal Transplants performed at UC San Diego and Rady Childrens Hospital
  • Outcome of bowel and bladder dysfunction in children utilizing behavioral and diet modification
  • Physiochemical Determinants of Odor Potency
  • The Men's Eating and Living (MEAL) Study: A Randomized Trial of Diet to Alter Disease Progression in Prostate Cancer Patients on Active Surveillance
  • The Role of Drain Placement in the Prevention of Complications Following Operative Management of Isolated Solid Organ Injury in Trauma
  • Endothelial activity in health and disease
  • Is Hypercholesterolemia a Risk Factor for Intrahepatic Cholangiocarcinoma (ICC), Extrahepatic Cholangiocarcinoma (ECC), and Gallbladder Cancer (GBCA)?
  • Lymphatic Malformations of the Head and Neck
  • The Role of Tamm-Horsfall Protein in Urinary Stone Disease
  • Pacemaker Insertion for the management of Arrhythmias in the Setting of Spinal Cord Injury
  • Effects of bariatric surgery on alcohol metabolism: Comparing gastric bypass, sleeve gastrectomy and laparoscopic gastric banding
  • Biosynthetic MEsh for Paraesophaegeal Hernia Repair- UCSD experience
  • Generation of Inducible pluripotent stem cells from skin fibroblasts
  • Comparison of Focused Abdominal Ultrasound in Trauma (FAST) in Combat Casualties and Civilian Major Trauma Victims
  • Incidence of dyspareunia after Transvaginal NOTES
  • A Validated Tool to Measure Satiety
  • Laparoscopic Sleeve Gastrectomy- UC San Diego experience
  • Role of Hedgehog Signaling in Hepatic Tumor-stroma Interactions: Implications for Vascular Invasion, Clinciopathological Staging and Patient Prognosis
  • Targeting Human Liver Pre-neoplastic Cells that Give Rise to Hepatocellular Carcinoma
  • The Injury and Traumatic Stress (INTRuST) Consortium Biorepository
  • Mining Gene Expression in Glue-grant Databases
  • Carotid Sinus Autonomic Response Mapping study (C-Map Study)
  • Comprehensive Umbrella of Research Experiences (CURE) Program
  • Pilot Study to Evaluate Hoarseness in Children with Kawasaki Disease
  • Prospective, Multicenter, Observational Study to Evaluate Single-Staged Open Complex Ventral Incisional hernia Repair Using a Bioabsorbable Material For Midline Fascial Closure Reinforcement
  • Respiratory Failure in Blunt Trauma Patients
  • The Use of Ultrasound in Determining the Presence of Bone Growth following Alveolar Bone/BMP Graft as a Part of Cleft Lip/Palate Treatment.
  • Role of Src/FAK pathway in blood brain barrier
  • Outcomes in pediatric urology: A PHIS analysis
  • The Use of Ultrasound in Determining the Presence of Bone Growth following Alveolar Bone/BMP Graft as a Part of Cleft Lip/Palate Treatment.
  • Profound Sudden Sensorineural Hearing Loss (SSNHL): A New Treatment Trial
  • Anosmia in Pediatric Population
  • Expression of Integrin avB3 may predict sensitivity to EGFR-targeted therapy in colorectal cancer (Sicklick and Cheresh, co-PI's)
  • Studying the effects of Truly mobile medical records on Patient Safety
  • Laparoscopic Roux en-Y Gastric Bypass-500 Patients: Complications with 3-60 month follow-up
  • Pre-hospital Care of Urban Gunshot Wound Patients
  • A Randomized, Double-Blind Study in the North American Region Comparing Prontosan vs. Saline in the Treatment of Chronic Wounds in Diabetic patients- An Exploratory pilot study.
  • Guidelines for the assessment of preoperative and postoperative endovascular aortic aneurysm repair (EVAR)
  • A Randomized Clinical Trial of Glyburide (RP=1127) for TBI
  • Salivary Gland Tumors in the Pediatric Population
  • Natural orifice Translumenal Endoscopic Surgery (NOTES): lacparoscopic Assisted NOTES Hepatobiliary Procedures, Trans-Vaginal and Trans-Gastric
  • Post-traumatic Renal Dysfunction
  • The development and implementation of a tool to measure marginalization, socialization and emotional challenges in reconstructive surgery patients.
  • Intra-Arterial injection of Bevacizumab for the Management of Glomus Jugulare Tumor
  • Developing a surgical risk-adjustment tool for resource-limited medical centers.
  • Evaluating the Role of a Rural vs. Urban Surgeon in Primary Care
  • Acquisition, Banking, and Analysis of Human Cell Lines for Use in Cancer and Non-cancer Research
  • A prospective Multicenter Trial to Evaluate Adhesion Characteristics and Adhesiolysis-Related Complications of Barrier-Coated and Non-barrier-Coated Intraperitoneal Mesh during Abdominal Re-Exploration After Prior Ventral Hernia Repair
  • Retrospective review of wrong level spine surgery before and after institution of intra-operative spinal time-out
  • Building Capacity for Emergency and Essential Surgical Care in Mozambique
  • Urinary Biomarkers for Childhood Appendicitis
  • Salivary Gland Tumors in the Pediatric Population
  • Surgical Techniques and Outcomes in Patients with Inflammatory Bowel Disease: A Retrospective
  • Enterra Therapy
  • Surgical Infection Society (SIS) Multicenter Study of Duration of Antibiotics for Intraabdominal Infection. R01 GM 081510-01
  • Surgical Outcomes Research Using Publicly Available Databases
  • Outpatient Appointments post Discharge and Their Link to Hospital Readmissions in Surgery patients
  • #101757 - Metabolic Surgery: Surgical Control of Type II Diabetes in Non Morbidly Obese Individuals
  • Esophageal Manometry Before and After Bariatric Surgery
  • Video Simulation for Surgical Robot can Differentiate between Experts and Novices
  • Histone Variant HPV-Related Cancer and Dysplasia
  • Inflammatory and Genetic Biomarkers of Neoplastic Transformation In Colorectal Cancer
  • Histone Variant in HPV-Related Cancer and Dysplasia
  • Use of Ultrasound as an Adjunct to Percutaneous Endoscopic Gastronomy (PEG) Insertion
  • Bioimplant Augmentation in the Soft Tissue Structures of the Foot and Ankle: A Multi-center Retrospective Review
  • Equine Pericardium for Treatment of Chronic and Difficult to Heal Wounds: Case Series
  • Study of Vascular biology and proteomics
  • Vesicoureteral Reflux Data Repository of Treatment and Outcomes, Retrospective and Prospective
  • Effect of Sleeve Gastrectomy on esophageal pH
  • Laparoscopic Gastric Plication for the Treatment of Obesity
  • SOLAS Spinal Surgery Registry: Prospective Clinical and Radiographic Outcomes Data Collection in Degenerative, Deformity and Trauma Patients
  • Efficacy of Electrical Stimulation for Dysphagia in Head and Neck Cancer Patients
  • Deaf Cultural Competency for Pharmacists
  • Study of Vascular biology and proteomics in explanted or resected organs
    Minimally Invasive Surgery plus rt-PA for ICH Evacuation (MISTIE)
  • Objective and Subjective Measures of Listening Effort for Speach Perception in Adult Cochlear Implant Users
  • Management of the Anticoagulated Traumatically Brain Injured Patient
  • Implicit attitudes of health care providers and their effect on racial and socioeconomic equity
  • A prospective, randomized, double blind, placebo-controlled, multicenter, Phase 2 study of OTO-104 given as a single intratympanic injection in subjects with unilateral Meniere's disease
  • Multi-Institutional Evaluation of the Current Management of Traumatic Pelvic Fracture
  • Defining Breast Reconstruction Rates After Total or Partial Mastectomy for Women of Varying Racial Backgrounds
  • Laparoscopic Sleeve Gastrectomy as a Treatment
  • Surgically Treated Hepatocellular Carcinoma:  A multicenter study
  • Study of Vascular Biology and Proteomics in explanted or resected organs
  • Economic Impact of Trauma
  • Clinical Utility of the FAST and Abdominal CT Scan in Trauma Patients
  • The Correlation Between Restless Leg Syndrome and Venous Insufficientcy
  • Postoperative Venous Thromboembolism Prophylaxis Patterns following Traumatic Spine Injuries
  • Generation of directed antibody library utilizing naive B-cells isolated form human tonsil
  • Topical Timolol for the Management of Recurrent Epistaxis in patients with Hereditary Hemorrahagic Telangiectasia (HHT)
  • Enoxaparin dosing for Venous Thromboembolism Prophylaxis in Trauma Patients
  • AMERICA: Axium MicroFX for Endovascular Repair of IntraCranial Aneurysm
  • Bioimplant Augmentation in the Soft Tissue Structures of the Foot and Ankle: A Multi-center Retrospective Review
  • Laparoscopic Sleeve Gastroectomy as a Treatment for Morbid Obesity in Adolescents
  • Evaluating Patient's Preferences in Minimally Invasive Colon Surgery
  • Stronger Communities through Effective Mentorship and Trauma Prevention: A collaboration between the UCSD Department of Surgery, and San Ysidro High School